Most organizations want to take advantage of the benefits offered by in-memory technologies that support their SAP BI and SAP BW needs in business analytics, operational and strategic reporting, and planning. One of the leading in-memory products on the market is SAP HANA. Over the course of my career, I have had some large organizations that I worked with decide not to implement SAP HANA because of concerns about anticipated high costs, lack of resources, and complexity. I review what it takes to implement and support SAP HANA-based BI architecture. Starting with a high-level overview of the SAP HANA infrastructure, I then explain the typical steps an organization has to go through to set it up and the costs associated with it. I also offer some tips for how to optimize infrastructure-related total cost of ownership (TCO).